You didn’t mention the ascendant so i will try to give some basic details.
Mars is for siblings , blood , courage, weapons & Land. Kethu is for spiritual, detachment , litigation & separation.
If native is male sure he will have separation & legal issues with his siblings. He has faced issues in his land & property. Native suffers blood related issues.
If native is female sure she will have separation or legal issues with her husband. She can’t get any marital pleasures from her husband. If there is no view of Guru or Venus marriage life will be ended with separation or divorce . She will have legal issues regarding her family property & lands.
If this combination is in 1 st place It will affects her health & thoughts.
In 2 nd place family life will be tragedy.
In 3 rd place native has no support of younger brothers. Native has separation with younger brothers or sisters.
In 4 th place it will affects health & relationship of mother.
In 5 th place native will have severe obstacles in getting of kids. Native will faces legal issues regarding family property. Natives love life will be ended with failure.
In 6 th place native has enmity with siblings. Blood related issues will come.
In 7 th place marriage life & marital pleasures will badly be affected.
In 8 th place native will be annoyed by negative thoughts & suicide thoughts.
In 9 th place father’s health & relationship will be affected.
In 10 th place native faces legal issues & obstacles in his job.
In 11 th place it will reduce the gain & benefit of native.
In 12 th place native will squandere his family assets. Native will spend money for his siblings & legal issues